Friday, December 12, 2008
Black and white is not always a clear distinction
"What I find fascinating about Obama's case is that people are asking questions about it," Saperstein said. "In the past, it wouldn't have been a question what he was, or how we should talk about him. There would have been no debate.
"We do need to take these issues into account when we study race," she said. "Race is not something you are. It is a very complex combination of factors that certainly does include things like skin tone, hair type and ancestry, but it also includes social status and our own stereotypes about people. Our study suggests that part of how we determine who is white is based on our assumptions about what white people do or what black people do. There is probably more mobility in our society by race than we acknowledge, because socioeconomic mobility often turns into racial mobility, where we define successful people as white and unsuccessful people as black."
The study's findings were drawn from a comprehensive examination of data that has been compiled as part of the National Longitudinal Survey of Youth that began in 1979 and continues today, tracking the same individuals. Saperstein and Penner focused on 1979 and 2002, comparing how participants identified themselves in both years and how they were labeled by interviewers each year between 1979 and 1998.
They found that 20 percent of the 12,686 respondents to the survey had at least one change in an interviewer's perception of their racial status during that span. Most of the interviews over the years occurred face-to-face, but the researchers found similar results when interviews were conducted by telephone.
The biggest change noted was that individuals who initially had been classified by interviewers as white were less likely to maintain that classification if they were later jailed, became unemployed or had been living below the poverty line. Researchers found that 96 percent of initially classified white respondents who were not incarcerated later still were identified as white, but that only 90 percent of whites who had been incarcerated in later years were still seen as white.
Nearly the same results held for self-identified classification, the researchers found, with 97 percent of whites in 1979 still saying they were white in 2002 if they had never been impoverished. However, just 93 percent of initially self-classified whites still said they were white in 2002 if they had fallen into poverty between the two years.
Respondents who self identified as black in 1979 and then went to prison were more likely to again say they were black in 2002 than were those who didn't go to prison in between, Saperstein said. "Those who went to prison were more likely to stay black, but those who didn't go to prison might move themselves to another identity."
Saperstein and Penner argue that racial identification can be altered by changes in social position, "much as a change in diet or stress level can alter a person's propensity to die of heart disease as opposed to cancer." In their conclusion, they write: "This suggests that racial stereotypes can become self-fulfilling prophesies: Although black Americans are overrepresented among the poor, the unemployed and the incarcerated, people who are poor, unemployed or incarcerated are also more likely to seen and identify as black and less likely to be seen and identify as white. Thus, not only does race shape social status, but social status shapes race." ###
About the University of Oregon
The University of Oregon is a world-class teaching and research institution and Oregon's flagship public university. The UO is a member of the Association of American Universities (AAU), an organization made up of 62 of the leading public and private research institutions in the United States and Canada. Membership in the AAU is by invitation only. The University of Oregon is one of only two AAU members in the Pacific Northwest.
Source: Aliya Saperstein, assistant professor of sociology, 541-346-8021 asaper@uoregon.edu
Links: Saperstein faculty Web page: sociology.uoregon.edu/faculty/saperstein;
sociology department: sociology.uoregon.edu/;
Penner faculty page: faculty.uci.edu/profile
Contact: Jim Barlow jebarlow@uoregon.edu 541-346-3481 University of Oregon
Wednesday, December 10, 2008
The Fresh Air Fund Helping inner city children
The Fresh Air Fund is an independent, not-for-profit agency that provides free summer vacations to New York City children from low-income communities. Jenny Morgenthau is the Executive Director.
More than 1.7 million children have been helped since 1877 and nearly 10,000 New York City children now enjoy free Fresh Air Fund programs annually. In 2006, 5,000 children visited volunteer host families in suburbs and small town communities across 13 states from Virginia to Maine and Canada; 3,000 children attended five summer camps on a 2,300-acre (9 km2) site in Fishkill, New York; and the fund’s year-round camping program serves an additional 2,000 young people each year.
In 2006, 75% of the total income of the fund came from private individuals.
The program
Each placement with a host family costs the fund $629 (2006).
Selection of children
Children are selected to participate based on financial need. Children are from low-income communities, with the majority receiving some form of public assistance. Youngsters are registered by more than 90 social service and community organizations in all five boroughs of New York City.
Host families
Volunteer host families open their homes to inner-city children for two weeks or more in the summertime. Each Friendly Town community is supervised by a committee of volunteers. Committee members select host families after reviewing their applications, visiting them in their homes and checking their personal references.
The camping program
Around 3,000 New York City youngsters, aged eight to fifteen, attend five Fresh Air camps on a 2,300-acre (9 km2) site in the Sharpe Reservation near Fishkill, New York.
* Camp Hidden Valley is for boys and girls with and without special needs, eight to twelve years old
* Camp Tommy (named after board member/designer Tommy Hilfiger for his dedication and support of Fresh Air children) is for boys aged twelve to fifteen
* Camp Anita Bliss Coler is for girls aged nine to twelve
* Camp Hayden-Marks Memorial is for boys aged nine to twelve
* Camp Mariah is a coed camp for youngsters aged twelve to fourteen (career campers)
Additionally, 2,000 young people participate in year-round weekend camping experiences.
Seven youngsters each year spend the summer at Camp Pioneer on the Sharpe Reservation, training to be counselors.
Career Awareness Program
The innovative Career Awareness Program is designed to help New York City youngsters understand the relationship between school and work and how to make choices that will determine their futures. Youngsters aged twelve to fourteen participate in job shadowing that offers a close-up view of business, and a career fair. The year-round program includes weekend camping trips and an intensive three-and-a-half week summer session at the Career Awareness Camp – Camp Mariah. The career camp is named in honor of Board member/singer Mariah Carey for her dedication, support and commitment to Fresh Air youngsters. Career awareness graduates continue to receive support through the PreOccupations Club and benefit from the guidance of volunteer mentors.
History of The Fund
In 1877, the Reverend Willard Parsons, minister of a small rural parish in Sherman, Pennsylvania, asked members of his congregation to provide country vacations as volunteer host families for children from New York City tenements. This was the beginning of the tradition. By 1884, Reverend Parsons was writing about the fund for the New York Tribune, and the number of children served grew. In 2006, close to 10,000 New York City children experienced the joys of summertime in Friendly Towns and at five Fund camps in upstate New York. When the New York Herald Tribune went out of business in 1966, the New York Times took over sponsorship.
New York City Volunteers
The fund has an active group of New York City volunteers. Metropolitan area volunteers help the fund reach out to New York City parents and children, support Camping, Career Awareness and Friendly Town programs and seek in-kind donations.
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article, Fresh Air Fund
Monday, December 8, 2008
Genetic ancestry of African-Americans reveals new insights about gene expression
Alkes Price, Assistant Professor of Epidemiology Department of Epidemiology Department of Biostatistics 665 Huntington Avenue Building 2, Room 211 Boston, Massachusetts 02115. 617.432.2262. aprice@hsph.harvard.edu | The amount of proteins produced in cells—a fundamental determinant of biological outcomes collectively known as gene expression—varies in African American individuals depending on their proportion of African or European genetic ancestry. These findings, by researchers based in Boston, Philadelphia and Oxford, are published December 5 in the open-access journal PLoS Genetics. Gene expression is known to vary among individuals and to be influenced by both genetic and environmental factors. Previous studies have reported gene expression differences among human populations, but it has been suggested that this could be due to non-genetic effects. |
In this study, the researchers show that gene expression levels in African Americans vary as a function of each individual's proportion of European ancestry. The differences due to ancestry (i.e. population differences between all Africans and all Europeans) were generally small—much smaller than differences between individuals within the same population; nevertheless, the authors were able to draw a distinction between effects of genetic ancestry at the location of the expressed gene (cis) and genetic ancestry elsewhere in the genome (trans). They conclude that only about 12% of heritable variation in human gene expression is due to cis regulation.
First author Alkes Price says, "It was a surprise that these conclusions could be drawn given that the differences due to genetic ancestry are so small." However, he cautioned that the results were confined to gene expression levels in a particular type of tissue known as lymphoblastoid cell lines, and have yet to be verified in other tissue types. ###
PLEASE ADD THIS LINK TO THE PUBLISHED ARTICLE IN ONLINE VERSIONS OF YOUR REPORT: dx.plos.org/10.1371/journal (link will go live on Friday, December 5)
CITATION: Price AL, Patterson N, Hancks DC, Myers S, Reich D, et al. (2008) Effects of cis and trans Genetic Ancestry on Gene Expression in African Americans. PLoS Genet 4(12): e1000294. doi:10.1371/journal.pgen.1000294
CONTACT: Alkes Price Assistant Professor, Departments of Epidemiology and Biostatistics Harvard School of Public Health aprice@hsph.harvard.edu
Disclaimer
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About PLoS Genetics
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About the Public Library of Science
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Contact: Mary Kohut Press@plos.org 415-568-3457 Public Library of Science
Saturday, December 6, 2008
Genetic variation increases HIV risk in Africans
Discussing the findings, Professor Weiss said: "The big message here is that something that protected against malaria in the past is now leaving the host more susceptible to HIV.
"In sub-Saharan Africa, the vast majority of people do not express DARC on their red blood cells and previous research has shown that this variation seems to have evolved to protect against a particular form of malaria. However, this protective effect actually leaves those with the variation more susceptible to HIV."
Lead author of the study, Professor Sunil K. Ahuja, from The University of Texas Health Science Center at San Antonio, added: "It turns out that having this variation is a double-edged sword. The finding is another valuable piece in the puzzle of HIV-AIDS genetics."
HIV affects 25 million people in sub-Saharan Africa today, an HIV burden greater than any other region of the world. Around 90 per cent of people in Africa carry the genetic variation, meaning that it may be responsible for an estimated 11 per cent of the HIV burden there. The authors observe that sexual behaviour and other social factors do not fully explain the large discrepancy in HIV prevalence in populations around the world, which is why genetic factors are a vital field of study. ###
Notes for Editors
1. Journalists seeking more information, or to interview Professor Robin Weiss, can contact Ruth Metcalfe in the UCL Media Relations Office on tel: +44 (0)20 7679 9739, mobile: +44 (0)7990 675 947, out of hours: +44 (0)7917 271 364, e-mail: r.metcalfe@ucl.ac.uk
2. The paper 'Duffy Antigen Receptor for Chemokines (DARC) Mediates Trans-infection of HIV-1 from Red Blood Cells to Target cells and Affects HIV-AIDS Susceptibility' is published in the journal Cell Host & Microbe, published by Cell Press. This is not an open-access journal but copies of the paper can be obtained from Ruth Metcalfe, UCL Media Relations, using the above contact details.
3. The authors of this paper are from: South Texas Veterans Health Care System, Texas, US; The University of Texas Health Science Center in San Antonio, US; UCL; Uniformed Services University, Maryland, US; Wilford Hall United States Air Force Medical Center, US and the San Antonio Military Medical Center.
4. In the UK, this work was supported by a grant to Professor Weiss from the Medical Research Council.
About UCL, Founded in 1826, UCL was the first English university established after Oxford and Cambridge, the first to admit students regardless of race, class, religion or gender, and the first to provide systematic teaching of law, architecture and medicine. In the government's most recent Research Assessment Exercise, 59 UCL departments achieved top ratings of 5* and 5, indicating research quality of international excellence.
UCL is in the top ten world universities in the 2007 THES-QS World University Rankings, and the fourth-ranked UK university in the 2007 league table of the top 500 world universities produced by the Shanghai Jiao Tong University. UCL alumni include Marie Stopes, Jonathan Dimbleby, Lord Woolf, Alexander Graham Bell, and members of the band Coldplay. www.ucl.ac.uk
Contact: Ruth Metcalfe r.metcalfe@ucl.ac.uk 020-767-99739 University College London
Thursday, December 4, 2008
More young black men have done prison time than served in the military or earned a college degree
Being jailed in federal or state prisons has become so common for African Americans today that more young black men in the United States have done time than have served in the military or earned a college degree, according to a new study.
The paper, appearing in the most recent American Sociological Review (published by the American Sociological Association), estimates that 20 percent of all black men born from 1965 to 1969 had served time in prison by the time they reached their early 30s. By comparison, less than 3 percent of white males born in the same time period had been in prison.
Equally startling, the risks of prison incarceration rose steeply with lower levels of education. Among blacks, 30.2 percent of those who didn't attend college had gone to prison by 1999 and 58.9 percent of black high school dropouts born from 1965 through 1969 had served time in state or federal prison by their early 30s.
By the end of 1999, 1.3 million men were in federal or state prisons. The researchers said that changes in penal policy through the 1970s and 1980s, including custodial sentences for drug offenses and mandatory minimum sentences, helped fuel the expansion of the penal system and has led to growing disparities in the risk of incarceration among men of different education levels.
"Prison is no longer just for the most violent or incorrigible offenders. Inmates are increasingly likely to be serving time for drug offenses or property crimes," Pettit said. "While there is enduring racial disproportionality in imprisonment, we find that the lifetime risk of incarceration is increasingly stratified by education. Over the past 30 years the risk of incarceration has grown for both blacks and whites, but has grown the fastest among men who have a high school diploma or less."
"This has become increasingly important because we know ex-prisoners face a variety of challenges after incarceration," said Western. "These range from employer discrimination in the job market to increased risks of divorce and separation in family life. The experience of imprisonment in America has emerged as a key social division, marking a new pattern in the lives of recent birth cohorts of black men." ###
The research was supported in part by the National Science Foundation and the Russell Sage Foundation.
Contact: Johanna Ebner / Lee Herring pubinfo@asanet.org 202-383-9005 x332 American Sociological Association
Tuesday, December 2, 2008
Archaeologists find evidence of earliest African slaves brought to new world
"This is the earliest documentation of the African Diaspora in the New World," says Price, a UW-Madison professor of anthropology. "It does mean that slaves were brought here almost as soon as Europeans arrived."
In early colonial Mexico, Campeche was an important Spanish gateway to the New World. It served as a base for exploration and conquest and was a key defensive outpost in a region infested with pirates. Presumably, slaves from the infamous West African port of Elmina were shipped to Campeche where they may have been used as domestic servants.
The discovery of the remains of slaves born in Africa from such an early date shows that slavery became an integral aspect of the New World economy not long after the Conquistadors completed the subjugation of Mexico, says Price.
Archaeological and historical evidence, including a map of colonial Campeche, suggest the graveyard was in use from about 1550 to the late 1600s. It was uncovered, along with the foundations of a colonial era church, in 2000 by construction workers digging around Campeche's central park. The site was excavated under the direction of Tiesler.
The archaeologists were drawn to some of the individuals buried in the colonial cemetery because of distinctive dental mutilations, a decorative practice characteristic of Africa.
Burton and Price, in collaboration with Tiesler, are conducting a much broader study of human mobility in ancient Mesoamerica using isotopic analysis. They conducted a blind study of the isotopic content of teeth from 10 individuals from the Campeche churchyard. Four of the samples, says Burton, "were like something we'd never seen."
The ratios, he explains, were well off the charts for anyone born in Mesoamerica. Instead, they reflected the geology of West Africa, which is underlain by a massive shield of ancient rock, much older than the geology of Mexico and Central America.
The chemical analysis, combined with the distinctive dental mutilation, provides strong evidence that "these folks were born in Africa and brought to the New World," says Price. " The thing that impresses me is that it was happening so early. "
African slaves were brought to the New World as the Spanish needed labor to harvest timber and work in the mines that enriched Spain. Early in their rule, the Spanish enslaved Indians to perform heavy labor, but they turned to the African slave trade as diseases introduced by Europeans decimated native peoples. ###
Terry Devitt, 608-262-8282, trdevitt@wisc.edu WEB: More news Photos
Contact: T. Douglas Price tdprice@wisc.edu 608-262-2575 University of Wisconsin-Madison
Sunday, November 30, 2008
Racism's cognitive toll: Subtle discrimination is more taxing on the brain
While certain expressions of racism are absent from our world today, you do not have to look very hard to know that more subtle forms of racism persist, in schools and workplaces and elsewhere. How do victims experience these more ambiguous racist messages" Are they less damaging than overt hostility" And what are the mental and emotional pathways by which these newer forms of discrimination actually cause personal harm"
Psychologists have some theories about how the experience of racism plays out in the brain—and what that means today compared to before. All human beings are driven by a few core needs, including the need to understand the world around us. When people do things to us, we must know why, and if we are uncertain we will spend whatever cognitive power we have available to diagnose the situation.
The problem is that we have limited cognitive resources, so when we are solving one problem, we have difficulty focusing on another at the same time. Some psychologists reason from this that subtle racism might actually be more, not less, damaging than the plain antipathy of yesterday, sapping more mental energy.
The experiment left no doubt about which candidate was best qualified, and sometimes that candidate was chosen, sometimes not. Sometimes the company passed over the best candidate for blatantly racist reasons; the reviewer might comment that the candidate belonged to “too many minority organizations,” for example. Other times the best candidate was simply passed over for no good reason. The psychologists ran the experiment many times, in every combination, so that both black and white volunteers saw black candidates reviewed by whites and by blacks and the same for white candidates.
After witnessing these fair and unfair hiring decisions, the study volunteers took the so-called Stroop test. During this test, the names of colors flash on the screen for an instant, but in the “wrong” colors (the word “red” in green letters, for example), and the idea is to quickly identify the color of the letters. It tests capacity for mental effort, and the idea in this study was to see if experiencing subtle racism interfered with that mental capacity.
It did, at least for blacks, and more than the overt racism did. As reported in the September issue of Psychological Science, black volunteers who had witnessed unfair but ambiguous hiring decisions did much less well on the Stroop test, suggesting that they were using all their mental resources to make sense of the unfairness. Interestingly, white volunteers were more impaired by overt racism than by the more ambiguous discrimination. Salvatore and Shelton figure this is because whites rarely experience any racism; they do not even notice the subtle forms of racism, and are thrown off balance when they are hit over the head by overt acts. Many blacks, by contrast, have developed coping strategies for the most hateful kinds of racism; it’s the constant, vague, just-below-the-surface acts of racism that impair performance, day in and day out. ###
Author Contact: Nicole Shelton nshelton@princeton.edu
Psychological Science is ranked among the top 10 general psychology journals for impact by the Institute for Scientific Information. For a copy of the article “Cognitive Costs of Exposure to Racial PRejudice” and access to other Psychological Science research findings, please contact Catherine West at (202) 783-2077 or cwest@psychologicalscience.org.
For more insights into human behavior, visit "We're Only Human . . ." at www.psychologicalscience.org/onlyhuman.
Contact: Catherine West cwest@psychologicalscience.org 202-783-2077 Association for Psychological Science
Friday, November 28, 2008
Race guides neighborhood evaluation, study says
The survey-based experiment involved more than 600 randomly selected white adults aged 21 and older living in the Chicago and Detroit metropolitan areas.
Participants were shown videos of various neighborhoods -- lower working class to upper class -- with actors posing as residents. Residents were portrayed doing exactly the same activities in each neighborhood, such as picking up mail or talking to neighbors.
While the survey participants viewed the same neighborhoods in the videos, they were randomly assigned to see white residents, black residents or a mix of both.
Participants were then asked to evaluate the neighborhoods in terms of housing cost, property upkeep, school quality, safety and future property values.
Whites who saw white residents in the video rated neighborhoods significantly more positively in four of the five dimensions when compared to whites who saw black residents in the identical neighborhood. Racially mixed neighborhoods fell in between.
"These findings demonstrate that 'objective' characteristics such as housing are not sufficient for whites to overcome the stereotypes they have about communities with African-American residents," said Krysan, who is also affiliated with the University of Illinois Institute of Government and Public Affairs.
Participants were also questioned regarding their endorsement or rejection of racial stereotypes. Whites who held negative stereotypes about blacks as a group were more likely to produce disapproving neighborhood evaluations.
According to the researchers, property value stagnation is one consequence of whites excluding neighborhoods solely due to the presence of black residents.
"This segregation limits occupational opportunities for blacks, ensures that blacks and whites will seldom have the chance to attend school together, and seriously limits the acquisition of wealth by African-Americans," said Michigan's Farley, who noted that racial segregation remains common in the older metropolises of the Midwest and Northeast.
Harvard University sociologist Lawrence Bobo, editor of the Du Bois Review, lauded the new study.
"It is rare to find research that combines high-quality new data with such grounded, real-world issues," he said. "Thanks to this highly innovative piece of research, we now understand far better than ever before the factors that create and sustain racial segregation of neighborhoods in America." ###
The study was funded by the National Science Foundation, the University of Michigan, the Ford Foundation, and UIC.
Established in 1948, the University of Michigan Institute for Social Research is among the world's oldest academic survey research organizations and a world leader in the development and application of social science methodology.
UIC ranks among the nation's top 50 universities in federal research funding and is Chicago's largest university with 25,000 students, 12,000 faculty and staff, 15 colleges and the state's major public medical center. A hallmark of the campus is the Great Cities Commitment, through which UIC faculty, students and staff engage with community, corporate, foundation and government partners in hundreds of programs to improve the quality of life in metropolitan areas around the world.
Contact: Brian Flood bflood@uic.edu 312-996-7681 University of Illinois at Chicago
Wednesday, November 26, 2008
Research demonstrates differing genetic makeup of lung cancer in African-American patients
Previous studies have determined that ethnicity can have an influence on the risk and outcome of non-small cell lung cancer patients, with African-American patients experiencing a higher risk and poorer outcomes. Ethnic background can also impact the genetic make-up and responsiveness of non-small cell lung cancer to EGFR gene blocking drugs. For example, a large number of Asian patients carry mutations of the EGFR gene than Caucasians, which can determine the likelihood of major clinical responses to EGFR inhibitor drugs while a higher copy number of EGFR is a predictor of better long-term outcome with the use of these drugs.
Researchers at the Departments of Medicine, Pathology and Biostatistics at Case Western Reserve University in Cleveland; the Departments of Medicine and Pathology at the University of Colorado Cancer Center in Aurora, Colo.; and the Instituto Clinico Humanitas IRCCS in Rozzano, Italy, sought to determine the frequency of EGFR abnormalities in African American patients since there is a paucity of data on this population.
The study authors observed 53 African-American patients with resected non-small cell lung cancer and found few EGFR mutations and an increase in the frequency of tumors with a high copy number of the EGFR gene. Previous studies have shown that an increase in the number of copies, regardless of mutation, predicts a better outcome with EGFR inhibitor drugs.
"The findings of this study were surprising since it was not expected that drug-sensitizing EGFR mutations would be so rare in this patient population," Rom Leidner, M.D., one of the study's authors and a clinical fellow in hematology/oncology at Case Western Reserve University said. "African-American patients remain underrepresented in clinical studies in oncology and therefore our knowledge base about how to modify our treatment strategies for this patient population remains poorly defined."
Researchers hope that the findings of their study could impact how clinical studies are designed in the future and how EGFR-targeted agents are used in the future. ###
The abstract, "A Study of Genetic Abnormalities of the EGFR Pathway in African American Patients with Non-Small Cell Lung Cancer," will be presented in a poster discussion session Friday, November 14, 2008 from 9:30 a.m. to 10:00 a.m. To speak to Dr. Leidner, please call Beth Bukata or Nicole Napoli on November 13-14, 2008, in the Press Room at the Chicago Marriott at 312-595-3177. You may also e-mail them at bethb@astro.org or nicolen@astro.org.
Contact: Beth Bukata bethb@astro.org 703-839-7332 American Society for Therapeutic Radiology and Oncology
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Monday, November 24, 2008
Hypertension develops early, silently, in African-American men
Kevin Heffernan, Ph.D. ostdoctoral Fellow Molecular Cardiology Research Center Tufts Medical Center 800 Washington Street, Box 080 Boston, MA 02111, 617-636-1441 Kevin Heffernan Kevin Heffernan was born and raised in the Bronx NY. He completed his BS in Exercise Science at the University of Scranton, his MS in Applied Physiology and Nutrition at Columbia University, and his PhD in Kinesiology/Exercise Physiology at the University of Illinois at Urbana-Champaign. Kevin has recently joined the Vascular Function Study Group in the Division of Cardiology. His research will focus on novel mechanisms influencing endothelial function and exercise capacity in patients with cardiovascular disease. When Kevin is not in the lab he enjoys resistance training, long walks on the beach and candlelit dinners. | Study points to central blood pressure as key to screening BETHESDA, Md. (Nov. 17, 2008) − Young and healthy African-American men have higher central blood pressure and their blood vessels are stiffer compared to their white counterparts, signs that the African American men are developing hypertension early and with little outward sign, according to a new study. While the study found that central blood pressure -- the pressure in the aorta, near the heart -- was higher in the African-American men, the study found no difference in brachial blood pressure -- measured on the arm -- between the two groups. Taken together, the findings suggest that hypertension (high blood pressure) may be developing undetected in young African-American men and that measuring central blood pressure may be a better means of detecting the problem as it develops. "Central blood pressure holds greater prognostic value than conventional brachial blood pressure as central pressure more aptly reflects the load encountered by the heart," the authors explained. "Thus, brachial blood pressure may neglect important information on cardiovascular burden and response to therapy in African-American men." |
'Silent killer'
African-American men have higher levels of hypertension than white men. Hypertension is known as the silent killer because it can develop without the individual knowing it. According to the U.S. Centers for Disease Control and Prevention, hypertension is a major risk factor for heart disease, stroke, congestive heart failure, and kidney disease. In 2002, hypertension was listed as a primary or contributing cause of death for 277,000 Americans.
The University of Illinois researchers hypothesized that the blood vessels of the black men would show greater dysfunction than the white men, even though both groups were young and equally healthy and fit. The vascular damage they looked for included stiffening and thickening of the blood vessels. These conditions result in pulsatile (not smooth) blood flow (and at higher pressure) to organs. The pressure can damage the organs over time.
Both groups healthy
The study included 55 young men, 30 white and 25 African-American. Most were university seniors. The average age was 23. There were no differences between the groups on a variety of measures, including heart rate, cardiorespiratory fitness, body mass index, body fat, blood lipids and glucose levels.
The researchers measured vascular function in a variety of ways, including:
* aortic blood pressure and stiffness
* brachial blood pressure
* carotid artery blood pressure
* carotid artery thickness and stiffness
They found the African-American men had similar brachial blood pressure, compared to the white men, but they had significantly higher:
* Central blood pressure, a measure of the pressure found in the artery, near the heart. The researchers used an instrument that takes blood pressure at the wrist and then calculates the central blood pressure.
* Carotid artery pressure. The carotid artery runs through the neck.
The African-American men, unlike the white men, also showed signs of early vascular damage that could lead to hypertension. For example, they had:
* Thicker carotid arteries, a sign of vascular damage that is usually found in older individuals and associated with atherosclerosis.
* Stiffer arteries, which are associated with high blood pressure. When the heart beats, blood flows through stiff arteries at greater speed and pressure. Elastic arteries provide a smoother blood flow and help prevent damage to organs receiving the blood and place less stress on the heart.
* Less change in diameter of the arteries when the heart beats, another measure of vascular stiffness. A healthy artery is more elastic will change in size as the blood flows through with each beat of the heart.
"Although having a similar cardiovascular risk factor profile as young white men, diffuse macrovascular and microvascular dysfunction is present at a young age in apparently healthy African American men," the authors wrote. "Values seen are comparable to values often reported in older individuals or individuals with more advanced hypertensive disease," they said.
These results do not shed light on why this happens to young and fit African-American men, Heffernan said. There may be environmental differences, such as differences in diet, which were not examined as part of this study, he said. ###
Editor's Notes: To arrange an interview with Dr. Heffernan, please contact Christine Guilfoy at cguilfoy@the-aps.org or (301) 634-7253.
A fuller audio interview with Dr. Heffernan is available in Episode 15 of the APS podcast, Life Lines, at www.lifelines.tv.
Funding: American Heart Association and the American College of Sports Medicine
Physiology is the study of how molecules, cells, tissues and organs function to create health or disease. The American Physiological Society (APS) has been an integral part of this scientific discovery process since it was established in 1887.
Find the full interview with Dr. Kevin Heffernan in Episode 15 of Life Lines. Interview begins at 13:26. The link is at lifelines.libsyn.com/
Contact: Christine Guilfoy cguilfoy@the-aps.org 301-634-7253 American Physiological Society
Saturday, November 22, 2008
African-Americans with depression and heart attack have greater risk of death
Using the Patient Health Questionnaire as part of a prospective myocardial infraction registry, Parashar and her team measured depressive symptoms in 397 African-American MI patients at Grady Memorial Hospital in metro Atlanta.
Patients were assessed and categorized as past, new, persistent or never depressed. Patients were followed up for a maximum of 58 months after MI. Researchers examined the relative prognostic importance of current, past versus persistent depression on mortality among African Americans with acute MI adjusting for demographic, clinical and quality of care variables.
Preliminary results show patients with persistent depression were almost three times as likely to die after MI compared with never depressed patients. ###
Contact: Juliette Merchant jmmerch@emory.edu 404-778-1503 Emory University
Thursday, November 20, 2008
Black entrepreneurs 4 times more likely to be refused credit than white businesses
Stuart Fraser, Associate Professor of Enterprise Centre for Small and Medium Sized Enterprises, Enterprise Group. Room D1.18 (Social Studies Building) Warwick Business School The University of Warwick Coventry, CV4 7AL, UK. | A research paper, by Dr Stuart Fraser of Warwick Business School at the University of Warwick, has found that many Ethnic Minority owned Businesses (EMBs) in the UK struggle to obtain credit in comparison to White owned businesses. Black and Bangladeshi owned businesses are the most likely to be refused credit, facing up to four times as many refusals as white owned businesses. Warwick Business School researcher Dr Stuart Fraser examined the small business credit market using data from the UK Survey of Small and Medium Finances (UKSMEF). He found that in particular Bangladeshi and Black owned firms are several times more likely to be denied loans than Indian and White owned businesses. The survey found that 36% of Black African firms had been denied loans compared to 29% of Black Caribbean, 20.6% of Bangladeshi, 12.2% Pakistani, 7.3% Indian, and 8.2% white owned businesses. |
The research found that one clear reason for this much higher incidence of missed loan repayments and exceeding overdraft limits (financial delinquency) was the much younger age of the Pakistani, Bangladeshi and Black owned firms compared to Indian and White firms. Black African owned businesses averaged 6 years, Black Caribbean 6.9, Bangladeshi, 6.5, Pakistani 8.3, Indian 14.2, and White owned 18.7 years. Other key reasons for financial delinquency include the business owner lacking a financial qualification or suitable financial advice and the business already having too much debt. In the case of Black African firms the research also points to cultural differences as a possible explanation for higher delinquency rates.
The research also found that Black Caribbean firms in the UK are less likely to apply for loans than White owned businesses due to fears of rejection based upon discrimination.
Dr Fraser points to the increasing use of 'arms length' credit and behavioural scoring systems, which do not allow transactions to be tainted by dubious judgements based upon ethnic perceptions by loan officers. He notes that scoring systems may explain the absence of racial bias, but ironically, they may also be responsible for misperceptions of racial bias since the reasons for rejection are not usually made clear to the applicant in these cases.
Dr Fraser says "Improvement in information flows between finance providers and businesses about the criteria used to make credit assessments including providing the reasons for rejection would help tackle the misperceptions of discrimination. In particular, finance providers should make it more clear to EMBs that defaulting on a loan or exceeding an overdraft limit could have adverse consequences for future credit."
This research highlights a number of factors which need to be addressed in order to reduce ethnic variations in loan denial rates: lack of financial skills and advice; poor financial performance; and ethnic and cultural differences. Targeting EMBs for assistance with skills advice may help reduce delinquency rates and improve access to finance. This, together with finance providers investing more in their relationships with Black firms could cause significant reductions in dissatisfaction. ###
Download the research paper: Is there Ethnic Discrimination in the UK Market for Small Business Credit?
For further information please contact: Peter Dunn, Press and Media Relations , University of Warwick Tel: +44 (0)24 76 523708 cell/mobile +44 (0)7767 655860 p.j.dunn@warwick.ac.uk Or Vincent Hammersley, Director of Communications
Warwick Business School Tel +44 (0) 2476 524124 Cell/Mobile +44 (0)7985 956624 Vin.Hammersley@wbs.ac.uk
Tuesday, November 18, 2008
Fear, misconceptions about screenings keep many African-Americans from getting mammograms
The findings are based on feedback gathered during focus groups that included 29 low-income African-American women who were at least 40 years old. The women were asked about their perception of mammograms, whether they would undergo one to screen for breast cancer, and other related questions.
Despite recommendations for women 40 and older to have annual mammograms, only 55 percent of the women reported having a mammogram within the last two years. One woman in the study had a history of breast cancer.
Participants in the study were low-income, medically underserved African-American women who lived in urban, economically challenged neighborhoods throughout Chicago. Participants received a $15 gift certificate to a grocery store in exchange for their participation.
Asked why they did not go for regular mammograms, women in the study gave several reasons. Some felt they had not been treated with respect or not received adequate information from clinical teams during prior visits to health care facilities.
One woman recounted feeling uncomfortable when she was left alone while her images were being developed and read by a radiologist.
"You see, when they left me, there wasn't nobody with me to talk to me," she said.
Other study participants said they thought anyone with breast cancer would inevitably die from the disease, so there was no use getting a mammogram.
"I didn't know that it was a possibility to live after you had breast cancer or had been found having breast cancer," one woman said.
"Everybody I know who had breast cancer [has] died. I [wasn't aware] of anything different," another woman said.
Women also said that stories circulate of patients who had bad experiences undergoing mammograms and received incorrect cancer treatments, such as an unnecessary mastectomy. Those tales are all spun into the urban folklore about mammograms and impact women's decisions not to get screened. The study adds that because of their fears, some women delay getting screened, which leads to worse health outcomes such as late-stage cancer diagnosis and higher mortality rates.
The study points to the need for physicians to be trained in cultural sensitivity. If health care providers tailored their care appropriately for this population, these patients may be more likely to return for repeat mammograms. The study also suggests the need for more community-based health educators to work within underserved communities, explaining the breast cancer screening process, addressing misperceptions, and reinforcing the health messages women receive from their physicians.
"African-American women have a high need for comprehensive information and better communication from their health care providers on breast cancer prevention and treatment. Sadly, we heard none of the women in our study were aware of early diagnosis or positive breast cancer outcomes," Peek said. ###
The study was funded by the Open Society Institute's Medicine as a Profession (MAP) fellowship program and Susan G. Komen for the Cure. Peek is currently supported by the Robert Wood Johnson Foundation Harold Amos Medical Faculty Development program.
Additional study authors include Judith Sayad and Ronald Markwardt.
Contact: Martha O'Connell Martha.OConnell@uchospitals.edu 773-834-8089
University of Chicago Medical Center
Sunday, November 16, 2008
Efforts for whites to appear colorblind may backfire
Tufts University researchers find that efforts to avoid the topic of race may have unintended results
MEDFORD/SOMERVILLE, Mass. -- New research shows that whites often avoid using race to describe other people, particularly in interactions with blacks. However further research reveals that such efforts to appear colorblind and unprejudiced are associated with less-friendly nonverbal behaviors.
"Many whites seem to think that appearing colorblind – avoiding race during social interaction – is a good way to appear unbiased," said Samuel R. Sommers, Ph.D., assistant professor of psychology in the School of Arts and Sciences at Tufts University. "Despite that perception that colorblindness may make a positive impression on others, our data suggests that it often backfires."
Claiming color blindness
In the first study, 57 white participants completed either a "sorting task" or a "hypothetical task." With the sorting task, participants sorted 24 photos of black and white volunteers according to seven characteristics: race, gender, age, color of the background in the photo, hair color, facial expression, and facial hair. In the hypothetical task, participants were asked to estimate how quickly they would categorize using each of the seven characteristics if they were to perform the sorting task.
The results for the sorting task showed that participants were quickest to categorize the photos by background color, then gender, then race. However, in the hypothetical task, participants estimated that the two slowest characteristics to determine would be race followed by age. Further research showed that blacks' speed at categorizing photos by race was comparable to whites' but their estimates of their ability to do this were more accurate than the estimates of white participants.
"Whites sometimes deny the ease with which they can categorize others by race," Sommers said. "And they'll even avoid using race as a simple descriptor of someone else."
Political correctness has surprising results
The second study examined some of the possible consequences of whites' reluctance to use race to differentiate people. Thirty white participants were randomly paired with a white or black partner who was in fact a "confederate" in the research project. The pair played a game in which one person asked questions to identify a target face in a set of photos. Questioners were told that their objective was to identify the photo the answerer was looking at by asking as few yes/no questions as possible.
The white participants, who all played the role of questioner, were given 32 photos of faces that varied by the same categories as those in the first study, including gender, background color and race. The "confederates" acted as answerers and were given a copy of the target photo. They answered yes or no questions until the questioner determined which of the 32 photos the answerer held.
The results showed that the questioner was less likely to mention race when the answerer was black (64 percent of the time) than when the answerer was white (93 percent of the time). This led to less-efficient performance times when white questioners were paired with black answerers because they asked more questions to identify the target photo.
In addition to slower performance, reluctance to differentiate by race was associated with less friendly nonverbal behaviors.
"When we showed independent coders video clips of questioners in the study without audio, they noted that the white participants who avoided talking about race with a black partner made less eye contact with their partners and appeared to be less friendly," Sommers said. "By their nonverbal behavior alone, the whites who are trying to appear colorblind to impress their black partners ironically come across as distant and unfriendly." ###
CONTACT: Kimberly M. Thurler kim.thurler@tufts.edu (617) 627-3175
Tufts University, located on three Massachusetts campuses in Boston, Medford, Somerville, and Grafton, and in Talloires, France, is recognized among the premier research universities in the United States. Tufts enjoys a global reputation for academic excellence and for the preparation of students as leaders in a wide range of professions. A growing number of innovative teaching and research initiatives span all Tufts campuses, and collaboration among the faculty and students in the undergraduate, graduate and professional programs across the university's eight schools is widely encouraged.
Contact: Suzanne Miller suzanne_c.miller@tufts.edu 617-627-4703 Tufts University
Friday, November 14, 2008
Gifts, affirmations boost medication adherence in African-Americans
PDF of Image | A patient education program that included self-affirmation and positive affect in the form of occasional gifts significantly increased medication adherence among African Americans with high blood pressure, according to research presented at the American Heart Association's Scientific Sessions 2008. The randomized, controlled trial found that calling patients occasionally with positive messages, coupled with standard information about hypertension encouraged them to take their medication more often than patients who received usual care. |
Adherence — taking medication consistently and correctly — is a major issue in all patient populations and especially African Americans.
"African Americans have been shown in some studies to be nearly twice as likely to not take their medicines when compared to Caucasians," Ogedegbe said.
For this study, researchers measured adherence, with electronic monitors installed on the caps of the blood pressure pill bottles. The monitors recorded each time the pill bottles were opened. Researchers consider this method far more reliable than patient self-report.
The study of 252 African Americans with hypertension found that those who received unexpected quarterly gifts by mail plus bi-monthly calls reminding them of positive life experiences took their medication 43 percent of the time over 12 months. Patients who just received a workbook on their disease with no additional intervention (control group) took their medicines 36 percent of the time during the year-long study.
"The adherence level is still woefully low," Ogedegbe said.
Of the study patients, 80 percent were women, average age 58. All were prescribed at least one anti-hypertension medication.
Although, most of the study participants were women, Ogedegbe expects the results to also apply to African-American men.
Each patient in the study in the intervention group and in the control group received a 10-chapter hypertension education workbook that detailed ways to combat hypertension. Those in the intervention group also were called every two months with homework from the workbook along with reminders to think about proud moments in their lives, their goals and the values they hold dear. The calls were not costly, Ogedegbe said, because they came from research assistants with college degrees rather than medical professionals.
The intervention group also received up to six small gifts unexpectedly throughout the 12-month study duration, which included an umbrella and a duffle bag. The items were adorned with positive messages such as, "It's a beautiful day."
"The whole idea is to reduce the amount of negativity patients have in terms of their health," Ogedegbe said. "If you are depressed, you are much less likely to take your medicine. This study attacked it from two ways by reducing the rate of depressed feelings and helping patients affirm their own positive feelings. When people receive unexpected good news or gifts it tends to induce positive feelings and it is shown to carry over into other areas of life." ###
Co-authors are: Carla Boutin-Foster, M.D; Martin T. Wells, Ph.D.; John P. Allegrante, Ph.D.; Jared B. Jobe, Ph.D.; and Mary E. Charlson, M.D.
Individual author disclosures can be found on the abstract.
The National Heart Lung and Blood Institute funded the study.
Statements and conclusions of study authors that are presented at American Heart Association scientific meetings are solely those of the study authors and do not necessarily reflect association policy or position. The association makes no representation or warranty as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing science content. Revenues from pharmaceutical and device corporations are available at www.americanheart.org/corporatefunding.
Contact: AHA News Media Staff Office bridgette.mcneill@heart.org 504-670-6524 American Heart Association
Wednesday, November 12, 2008
Blood Pressure Control Inequality Linked to Deaths Among Blacks
Kevin Fiscella, M.D., M.P.H. Associate Professor of Family Medicine and Community & Preventive Medicine with tenure, University of Rochester School of Medicine & Dentistry Associate Director, Rochester Center to Improve Communication in Health Care HIV Clinical Coordinator, Westside Community Health Center | Racial disparity in the control of hypertension contributes to the deaths of almost 8,000 black men and women in the United States annually, according to a first-of-its-kind study published today in the Annals of Family Medicine by University of Rochester Medical Center researchers. The researchers concluded that the deaths could be avoided or postponed if blacks had their hypertension, or high blood pressure, controlled to the same level as whites. “Disparity in the control of blood pressure is one of the most important, if not the most important, contributor to racial disparity in cardiovascular mortality, and probably overall mortality,” said Kevin Fiscella, M.D., M.P.H., lead author of the article and associate professor of family medicine and of community and preventive medicine at the Medical Center. “If we as clinicians are going to reduce cardiovascular and stroke-related deaths, we need to pay attention to all the barriers to improving blood pressure control, particularly for minority patients” Fiscella said. Although not clearly known, the likely causes of the racial disparity include differences in access to care, clinician management and communication, hypertension severity, and patient adherence. |
“There is evidence from previous studies that access barriers and financial and interpersonal communication barriers affect the ability of black patients to get medical care or to take their medication as prescribed,” Fiscella said.
Fiscella and Kathleen Holt, Ph.D., adjunct professor of community and preventive medicine at the Medical Center, are authors of the articles, which is the first effort to quantify the toll of racial disparity in blood pressure control. The article is part of a package of articles on racial disparity in the Annals of Family Medicine that is accompanied by editorials from former U.S. Surgeon General David Satcher, M.D., Ph.D., and Crystal Wile Cené, M.D., M.P.H., and Lisa A. Cooper, M.D., M.P.H. They call on clinicians, researchers, health care administrators, health care planners and policy makers to work together to gain a better understanding of the barriers faced by ethnic minorities.
Hypertension is a precursor to cardiovascular disease, which is the leading cause of death in the United States and which occurs at the highest rate among black Americans.
The researchers analyzed data of 1,545 black adults and 1,335 white adults. The mean blood pressure among blacks with hypertension was approximately six mm/Hg (millimeters of mercury) higher than that for the total adult black population and seven mm/Hg higher than that for whites with hypertension.
A reduction in mean blood pressure among blacks to that of whites would reduce the annual number of deaths among blacks from heart disease by 5,480 and from stroke by 2,190, the researchers concluded.
“There is evidence for racial disparity in patient adherence to antihypertensive medication, including studies conducted within the Veterans Administration Health System, where fewer differences in access appear to exist,” the researchers state in the article. “Differences in adherence by race may be due to affordability of medicines, personal beliefs, anticipated adverse effects, and health literacy that disproportionately affect blacks. Although multiple causes may contribute to racial disparity in blood pressure control, this disparity is not inevitable. Disparity in hypertension control is significantly smaller in the Veterans Administration Health System, where access barriers are fewer.”
Elimination of racial disparity in blood pressure control is an attainable goal, provided sufficient resources are available to discover and address adherence barriers, the researchers conclude.
Funding for the research was provided by the Robert Wood Johnson Foundation and through a grant from the National Heart, Lung, and Blood Institute.
Contact: Michael Wentzel Michael_Wentzel@urmc.rochester.edu 585-275-1309 University of Rochester Medical Center
Monday, November 10, 2008
ERSD, heart disease and African-Americans with hypertensive nephrosclerosis
For most patients with chronic kidney disease (CKD), the risk of experiencing a cardiovascular related death is greater than the risk of progressing to end-stage renal disease (ESRD).
According to research being presented at the American Society of Nephrology's 41st Annual Meeting and Scientific Exposition in Philadelphia, Pennsylvania, African Americans with CKD caused by high blood pressure (hypertensive nephrosclerosis) demonstrated a higher risk of progressing to ESRD than dying from heart disease related events.
Tahira Alves, MD, of Vanderbilt University in Nashville, Tennessee, will present the cardiovascular and renal results from the AASK (African American Study of Kidney Disease) Cohort Study (2002-2007), which followed the original AASK Trial (1996-2001).
The risk of death from cardiovascular disease was 0.8 per 100 patient-years. Of 74 deaths that occurred during the Cohort period of the AASK Study, more than 60 percent were from causes other than cardiovascular disease.
The finding that ESRD risk is higher than cardiovascular risk for African Americans with hypertensive nephrosclerosis is in direct contrast to what has been previously reported in other CKD populations. "The AASK trial and the subsequent cohort study allow the medical community to gain a broader understanding of incident cardiovascular disease and mortality during long-term follow-up in an entirely African-American population with nondiabetic hypertensive nephrosclerosis," comments Dr. Alves.
The findings are limited by the fact that the primary goal of the AASK trial was to detect changes in kidney function, ESRD, and/or risk of death. Cardiovascular events were measured as a secondary outcome.
The results may provide additional insight into the relationship between high blood pressure and kidney disease in African Americans, as well as some of the reported racial differences in the rates and outcomes of ESRD. "The study is timely given the increased recognition of medical health disparities observed among African American patients," Dr. Alves adds. "This type of information is needed if solutions are to be sought at the clinical and policy levels." ###
The AASK studies were sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health.
The study abstract, "African-Americans (AA) with Hypertensive Nephrosclerosis Are Paradoxically More Likely To Reach End Stage Renal Disease (ESRD) Than Have a Cardiovascular Event," (TH-FC051) will be presented as part of a Free Communications session on the topic of "Effects of Traditional and Nontraditional Risk Factors on Cardiovascular Risk in Chronic Kidney Disease and End Stage Renal Disease" on Thursday, November 6, at 5:36 p.m. in Room 108 of the Pennsylvania Convention Center in Philadelphia, PA.
ASN is a not-for-profit organization of 11,000 physicians and scientists dedicated to the study of nephrology and committed to providing a forum for the promulgation of information regarding the latest research and clinical findings on kidney disease. ASN Renal Week 2008, the largest nephrology meeting of its kind, will provide a forum for 11,000 nephrologists to discuss the latest findings in renal research and engage in educational sessions related to advances in the care of patients with kidney and related disorders. Renal Week 2008 will take place November 4 – November 9 at the Pennsylvania Convention Center in Philadelphia, PA.
Contact: Shari Leventhal sleventhal@asn-online.org WEB: American Society of Nephrology
Saturday, November 8, 2008
Family problems affect African-American children more than other races
Stephen M. Gavazzi of The Ohio State University, Jennifer M. Bostic and Courtney M. Yarcheck of the OSU Center for Family Research, and Ji-Young Lim of Miami University of Ohio examined factors related to gender, race/ethnicity, family factors, and mental health issues is a sample of 2,549 Caucasian and African American youth coming to the attention of juvenile courts. ###
This study is published in the Journal of Marital and Family Therapy. Media wishing to receive a PDF of this article may contact journalnews@bos.blackwellpublishing.net.
Stephen Gavazzi is affiliated with The Ohio State University and can be reached for questions at gavazzi.1@osu.edu.
The Journal of Marital & Family Therapy (JMFT) is published quarterly by the American Association for Marriage and Family Therapy (AAMFT) and, with over 20,000 subscribers, is the best known and most influential family therapy journal in the world.
Wiley-Blackwell was formed in February 2007 as a result of the acquisition of Blackwell Publishing Ltd. by John Wiley & Sons, Inc., and its merger with Wiley's Scientific, Technical, and Medical business. Together, the companies have created a global publishing business with deep strength in every major academic and professional field. Wiley-Blackwell publishes approximately 1,400 scholarly peer-reviewed journals and an extensive collection of books with global appeal. For more information on Wiley-Blackwell, please visit www.wiley-blackwell.com or interscience.wiley.com.
Contact: Amy Molnar journalnews@bos.blackwellpublishing.net 201-748-8844 Wiley-Blackwell